“Hot Paper” in Chemistry - A European Journal

Our new paper on modelling the inhibition of selenoproteins by small molecules using cysteine and selenocysteine derivatives has been selected as a "Hot Paper" in Chemistry - A European Journal. We demonstrate, for the first time, that the arylselenium species eliminated from the selenocysteine derivatives exhibit significant redox activity, which may have a significant effect on the cellular redox state during the inhibition of selenoproteins.