Mugesh has been selected for the Infosys Prize 2019
November 7, 2019
Mugesh has been selected for the Infosys Prize in Physical Sciences for the year 2019. He has been selected for this award for his pioneering work in the chemical synthesis of small molecules and nanomaterials for biomedical applications.
Namrata Singh receives the IIT Bombay Metrohm Young Chemist Award
September 17, 2019
Namrata Singh has been awarded the IIT Bombay Metrohm Young Chemist Award 2019 for "Innovation in Research" at an award ceremony held at IIT Bombay on September 17, 2019. The award was given for her research on uncovering the role of an antioxidant nanozyme that provides cytoprotection in Parkinson’s Disease model.
Highlight on the Cover Page of Chemistry - A European Journal
August 7, 2019
Our paper published in collaboration with Dr Kenta Arai and Prof. Michio Iwaoka on "Modeling Thioredoxin Reductase‐Like Activity with Cyclic Selenenyl Sulfides: Participation of an NH⋅⋅⋅Se Hydrogen Bond through Stabilization of the Mixed Se−S Intermediate" is highlighted on the Cover of Chemistry - An European Journal.
“Reviews Showcase” in Chemistry - A European Journal
July 2, 2019
Our recent concept article on Directing Traffic: Halogen-Bond-Mediated Membrane Transport has been selected by the Editorial Office for the Showcase of outstanding Review-type articles in Chemistry - A European Journal. In this article, we describe a novel strategy involving halogen bonding for increasing the cellular uptake of small molecules and proteins.
Our new paper on modelling the inhibition of selenoproteins by small molecules using cysteine and selenocysteine derivatives has been selected as a "Hot Paper" in Chemistry - A European Journal. We demonstrate, for the first time, that the arylselenium species eliminated from the selenocysteine derivatives exhibit significant redox activity, which may have a significant effect on the cellular redox state during the inhibition of selenoproteins.
Our new paper on membrane transport of green fluorescent protein in mammalian cells has been selected as a "Hot Paper" in Angewandte Chemie. We show that the introduction of an iodine atom to one of the tyrosine residues facilitates the cellular entry of green fluorescent proteins, providing a strategy for the delivery of macromolecules into mammalian cells.
In a first, IISc team directly delivers protein into cells - The Hindu
April 21, 2019
In a breakthrough that might have huge medical implications, researchers at Bengaluru’s Indian Institute of Science (IISc) have used a novel strategy to directly deliver proteins into mammalian cells. Proteins are big molecules and so cannot enter the cells on their own. So a team from the institute’s Department of Inorganic and Physical Chemistry substituted a hydrogen atom of the protein with an iodine atom to achieve a nearly sixfold increase in protein uptake by cells.
ChemistryViews: Halogen-Mediated Transport through Cell Membranes
March 8, 2019
Our work on Halogen-Mediated Membrane Transport, published in Chemistry - A European Journal has been featured on ChemistryViews, Wiley-VCH's chemistry portal. We found that the introduction of iodine atoms into a series of fluorescent molecules (example pictured) remarkably enhances the cellular uptake. Using two iodine atoms, the cellular uptake can be increased to more than 95 % in mammalian cells.
Namrata Singh has been awarded an ACS Poster Prize at the CRSI-NSC-24
February 10, 2019
Namrata Singh has been awarded an ACS poster prize for her work titled "A manganese-based nanozyme for cellular redox regulation", at the 24th CRSI National Symposium in Chemistry (NSC-24), at CLRI, Chennai, during February 8 - 10, 2019.
CRSI Silver Medal by the Chemical Research Society of India
February 9, 2019
Mugesh has been awarded the CRSI Silver Medal for the year 2019 by the Chemical Research Society of India. He delivered the Medal Lecture at the 24th National Symposium in Chemistry held at CLRI, Chennai, during February 8-10, 2019.
“Very Important Paper (VIP)” in Chemistry - A European Journal
February 4, 2019
According to the evaluation of referees, our paper titled "Halogen-Mediated Membrane Transport: An Efficient Strategy for the Enhancement of Cellular Uptake of Synthetic Molecules", has been designated as Very Important Paper (VIP). Less than 5% of the manuscripts accepted for publication in the journal receive such a positive review.
Punarbasu Roy has been awarded a Poster Prize at the I-DEC-2018
December 8, 2018
Punarbasu Roy has been awarded a poster prize (RSC-Chem.Comm.) for his work titled "Mechanistic investigation of GPx-like activity of V2O5 nanozyme", at the Inter-Disciplinary Explorations in Chemistry (I-DEC-2018) at IISER Bhopal, during December 6 - 8, 2018.
Prof. R.C. Mehrotra Commemoration Lecture Award of ISCA
November 27, 2018
Mugesh has been selected for Prof. R.C. Mehrotra Commemoration Lecture Gold Medal of the Indian Science Congress Association (ISCA) for the year 2018-19. He has been invited to deliver the Award Lecture at the 106th Indian Science Congress to be held during January 3-7, 2019.
Sourav Ghosh has been awarded a Poster Prize at the CRSI-NSC-23
July 15, 2018
Sourav Ghosh has been awarded a poster prize for his work titled "Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2O5 Nanomaterials," at the 23rd CRSI National Symposium in Chemistry (NSC-23) at IISER Bhopal, during July 13 - 15, 2018.
Author Profile in Angewandte Chemie
August 30, 2018
“When I was eighteen I wanted to be a farmer. The natural talent I would like to be gifted with is the ability to learn new languages quickly …” Find out more about Govindasamy Mugesh in his Author Profile.