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​PUBLICATIONS 2009-2013

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104. Vernekar, A. A.; Mugesh, G.* Catalytic Reduction of Graphene Oxide Nanosheets by Glutathione Peroxidase Mimetics reveals a New Structural Motif in Graphene Oxide.
Chem. Eur. J., 2013, 19, 16699 - 16706. Read more....
[Highlighted in the "Hot Topics" section of Wiley-VCH].

 

103. Manna, D.; Roy, G.; Mugesh, G.* Antithyroid Drugs and their Analogues: Synthesis, Structure and Mechanism of Action.
Acc. Chem. Res., 2013, 11, 2706 - 2715. Read more....

 

102. Rijntjes, E.*; Scholz, P. M.; Mugesh, G.; Koehrle, J. Se- and S-based thiouracil and methimazole analogues exert different inhibitory mechanisms on type 1 and type 2 deiodinases.
Eur. Thyroid J., 2013, 2, 252 - 258. Read more...

 

101. Tan, S.M.; Sharma, A.; Yuen, D. Y. C.; Stefanovic, N.; Krippner, G.; Mugesh, G.; Chai, Z.; de Haan. J. B.* The modified selenenyl amide, m-hydroxy ebselen, attenuates diabetic nephropathy and diabetes-associated atherosclerosis in ApoE/GPx1 double knockout mice.
PLOS ONE, 2013, 8, 0000 - 0000. Read more...

 

100. Roy, G.*; Jayaram, P. N.; Mugesh, G.* Inhibition of Lactoperoxidase-catalyzed Oxidation by Imidazole-based Thiones and Selones: A Mechanistic Study.
Chem. Asian J., 2013, 8, 1910 - 1921. Read more...
[Asian Chemical Congress Special Issue. Read the Editorial here].

 

99. Bhabak, K. P.; Bhowmick, D.; Mugesh, G.* Synthetic Glutathione Peroxidase Mimics: Effect of Nucleophilicity of the Aryl Thiol Cofactor on the Antioxidant Activity.
Ind. J. Chem. 2013, 52A, 1019 - 1025. Read more...
[Invited article for a special issue: Complex Chemical Systems].

 

98. Bhowmick, D.; Mugesh, G.*'Enzyme mimetic chemistry of organoselenium compounds', in The Chemistry of Organic Selenium and Tellurium Compounds, Volume 4, edited by Z. Rappoport. John Wiley & Sons, Ltd: Chichester, UK, pp. 1175-1235, 2013.

 

97. Mugesh, G.* Glutathione Peroxidase Activity of Ebselen and its Analogues: Some Insights into the Complex Chemical Mechanisms Underlying the Antioxidant Activity.
Curr. Chem. Biol., 2013, 7, 47 - 56. Read more...
[Invited article for a Special Issue: Selenium Antioxidants].

 

96. Jakka, S. R.; Mugesh, G.* The role of sulfur and selenium species in the thyroid, in "Handbook of Chalcogen Chemistry: New Perspectives in Sulfur, Selenium and Tellurium (2nd Edition)". Eds. Devillanova, F. A.; du Mont, W.-W., The Royal Society of Chemistry, 2013, p47-65.

 

95. Bhuyan, B. J.; Lamani, D. S.; Mugesh, G.*; Wirth, T.* Current research on mimics and models of selenium-containing antioxidants, in "Handbook of Chalcogen Chemistry: New Perspectives in Sulfur, Selenium and Tellurium (2nd Edition)". Eds. Devillanova, F. A.; du Mont, W.-W., The Royal Society of Chemistry, 2013, p25-46.

 

94. Bhowmick, D.; Mugesh, G.* Tertiary Amine-based Glutathione Peroxidase Mimics: Some Insights into the Role of Steric and Electronic Effects on Antioxidant Activity.
Tetrahedron, 2012, 68, 10550 - 10560. Read more....

 

93. Lamani, D. S.; Bhowmick, D.; Mugesh, G.* Spirodiazaselenuranes: Synthesis, Structure and Antioxidant Activity.
Org. Biomol. Chem., 2012, 10, 7933 - 7943. Read more....

 

92. Vernekar, A. A.; Mugesh, G.* Hemin-Functionalized Reduced Graphene Oxide Nanosheets Reveal Peroxynitrite Reduction and Isomerization Activity.
Chem. Eur. J., 2012, 18, 15122 - 15132. Read more....
[Highlighted in the "Hot Topics" section of Wiley-VCH].

 

91. Manna, D.; Mugesh, G.* Regioselective Deiodination of Thyroxine by Iodothyronine Deiodinase Mimics: An Unusual Mechanistic Pathway Involving Cooperative Chalcogen and Halogen Bonding.
J. Am. Chem. Soc., 2012, 134, 4269 - 4279. [Abstract].
[This work has been highlighted as News & Views in Nature Chemistry].

 

90. Singh, M.; Butcher, R. J.; Jasinski, J. P.; Golen, J. A.; Mugesh, G.* Synthesis, Characterization and Phosphotriesterase Mimetic Activity of Some Zn(II) and Cu(II) Complexes.
J. Chem. Sci., 2012, 124, 1301 - 1313. Read more....
[Invited article for a Special Issue: 14th Modern Trends in Inorganic Chemistry].

 

89. Mahata, S.; Maru, S.; Shukla, S.; Pandey, A.; Mugesh, G.; Das, B. C.; Bharti, A. C.* Anticancer property of Bryophyllum pinnata (Lam.) Oken. leaf on human cervical cancer cells.
BMC Complement. Altern. Med. 2012, 12, 1-15. Read more....

 

88. Bhuyan, B. J.; Mugesh, G.* Antioxidant Activity of Peptide-based Angiotensin Converting
Enzyme Inhibitors.

Org. Biomol. Chem., 2012, 10, 2237 - 2247. Read more....

 

87. Umayal, M.; Tamilselvi, A.; Mugesh, G.* Metallo-b-lactamases and their Synthetic Mimics: Structure, Function and Catalytic Mechanism.
Prog. Inorg. Chem., 2012, 57, 395 - 443. Read more....

 

86. Bhabak, K. P.; Mugesh, G.* Synthetic Mimics of Selenoproteins, in "Selenoproteins and Mimics". Eds. Liu, J.; Luo, G., Zhejiang University Press, Hangzhou and Springer-Verlag Berlin Heidelberg, 2012, p207-221.

 

85. Bhabak, K. P.; Mugesh, G.* Gold(I)-Selenolate Complexes: Synthesis, Characterization and Ligand Exchange Reactions.
J. Chem. Sci., 2011, 123, 783 - 789. Read more....
[International Year of Chemistry: Invited article for a Special Issue].

 

84. Bhabak, K. P.; Satheeshkumar, K.; Jayavelu, S.; Mugesh, G.* Inhibition of Peroxynitrite- and Peroxidase-mediated Protein Tyrosine Nitration by Imidazole-based Thiourea and Selenourea Derivatives.
Org. Biomol. Chem., 2011, 9, 7343 - 7350. Read more....

 

83. Akif, M.; Masuyer, G.; Schwager, S.; Bhuyan, B. J.; Mugesh, G.; Isaac, E. R.; Sturrock, E.; Acharya, R.K.* Structural Characterization of Angiotensin-I Converting Enzyme in Complex with a Selenium Analogue of Captopril.
FEBS Journal, 2011, 278, 3644 - 3650. Read more....
[This paper has been highlighted in the Molecular Enzymology Virtual Special Issue].

 

82. Manna, D.; Mugesh, G.* Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics: Does an Increase in the Reactivity Alter the Regioselectivity?
J. Am. Chem. Soc., 2011, 133, 9980 - 9983. Read more....

 

81. Bhuyan, B. J.; Mugesh, G.* Angiotensin Converting Enzyme Inhibitors in the Treatment of Hypertension.
Current Science, 2011, 101, 881 - 887. Read more....
[Invited article for a special section "Chemistry - Synthesis, Structure and Dynamics"].

 

80. Bhabak, K. P.; Mugesh, G.* Synthesis and Characterization of Some Gold(I)-Thiolate Complexes Having N-Methylimidazole Moiety
Ind. J. Chem. 2011, 50A, 1303 - 1307. Read more....
[Invited article for a special issue dedicated to A. P. C. Ray on his 150th birth anniversary].

 

79. Roy, G.; Bhabak, K. P.; Mugesh, G.* Interactions of Antithyroid Drugs and their Analogues with Halogens and their Biological Implications.
Crystal Growth & Design, 2011, 11, 2279 - 2286. Read more....
[Invited article for Structural Chemistry in India: Emerging Themes].

 

78. Bhabak, K. P.; Vernekar, A. A.; Jakka, S. R.; Roy, G.; Mugesh, G.* Mechanistic Investigations on the Efficient Catalytic Decomposition of Peroxynitrite by Ebselen Analogues.
Org. Biomol. Chem., 2011, 9, 5193 - 5200. Read more....

 

77. Bhuyan, B. J.; Mugesh, G.* Effect of Peptide-based Captopril Analogues on Angiotensin Converting Enzyme Activity and Peroxynitrite-mediated Tyrosine Nitration.
Org. Biomol. Chem., 2011, 9, 5185 - 5192. Read more....

 

76. Bhabak, K. P.; Bhuyan, B. J.; Mugesh, G.* Bioinorganic and Medicinal Chemistry: Aspects of Gold(I)-Protein Complexes.
Dalton Trans. 2011, 40, 2099 - 2111. Read more....
[Invited Perspectives article for a special issue "New Talent: Asia"].

[This paper is one of the Top 10 Most-read Dalton Transactions articles in February 2011].

 

75. Satheeshkumar, K.; Mugesh, G.* Synthesis and Antioxidant Activity of Peptide-based Ebselen
Analogues.

Chem. Eur. J., 2011, 17, 4849 - 4857. Read more....

 

74. Umayal, M.; Mugesh, G.* Metallo-b-lactamase and Phosphotriesterase Activities of Some Zinc(II) Complexes.
Inorg. Chim. Acta, 2011, 372, 353 - 361. Read more....
[Special issue dedicated to Prof. S. S. Krishnamurthy on the occasion of his 70th birthday.]

 

73. Tamilselvi, A.; Mugesh, G.* Metallo-b-lactamase-Catalyzed Hydrolysis of Cephalosporins: Some Mechanistic Insights into the Effect of Heterocyclic Thiones on Enzyme Activity.
Inorg. Chem., 2011, 50, 749 - 756. Read more....

 

72. Bhuyan, B. J.; Mugesh, G.* Synthesis, Characterization and Antioxidant Activity of Angiotensin Converting Enzyme Inhibitors.
Org. Biomol. Chem., 2011, 9, 1356 - 1365. Read more....
[This paper has been selected as a Hot Article]

[This work has been featured on the Cover Page of the Journal]

 

71. Jakka, S. R.; Mugesh, G.* Effect of b-Lactamase-catalyzed Hydrolysis of Cephalosporins on Peroxynitrite-Mediated Nitration of Serum Albumin and Cytochrome c.
Ind. J. Chem. 2011, 50A, 447 - 452. Read more....
[Invited article for a special issue on Bioinorganic Chemistry].

 

70. Bhuyan, B. J.; Mugesh, G.* Biological and Biochemical Aspects of Selenium Compounds, In Organoselenium Chemistry: Synthesis and Reactions. Ed. Wirth, T.; Wiley-VCH Verlag GmbH & Co. KGaA, 2011, p 361-392.

 

69. Seminario-Vidal, L.; van Heusden, C.; Mugesh, G.; Lazarowski, E. R.* Ebselen is a potent non-competitive inhibitor of extracellular nucleoside diphosphokinase.
Purinergic Signalling, 2010, 6, 383 - 391. Read more....

 

68. Manna, D.; Mugesh, G.* A Chemical Model for the Inner-Ring Deiodination of Thyroxine
by Iodothyronine Deiodinase.

Angew. Chem. Int. Ed., 2010, 49, 9246 - 9249. Read more....

 

67. Bhabak, K. P.; Mugesh, G.* Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants.
Acc. Chem. Res., 2010, 43, 1408 - 1419. Read more....
[This work has been featured on the Cover Page of the Journal]

 

66. Tamilselvi, A.; Mugesh, G.* Hydrolysis of Organophosphate Esters: Phosphotriesterase Activity of Metallo-b-lactamase and Its Functional Mimics.
Chem. Eur. J., 2010, 16, 8878 - 8886. Read more....

 

65. Sarma, B. K.; Manna, D.; Minoura, M.; Mugesh, G.* Synthesis, Structure, Spirocyclization Mechanism and Glutathione Peroxidase-like Antioxidant Activity of Stable Spirodiazaselenurane and Spirodiazatellurane.
J. Am. Chem. Soc., 2010, 132, 5364 - 5374. Read more....

 

64. Tamilselvi, A.; Mugesh, G.* Interaction of Heterocyclic Thiols/Thiones Eliminated from Cephalosporins with Iodine and its Biological Implications.
Bioorg. Med. Chem. Lett., 2010, 20, 3692 - 3697. Read more....

 

63. Bhabak, K. P.; Mugesh, G.* Inhibition of Peroxidase-catalyzed Protein Tyrosine Nitration by Antithyroid Drugs and their Analogues.
Inorg. Chim. Acta, 2010, 363, 2812 - 2818.Read more....
[Special issue dedicated to Prof. Animesh Chakravorty on the occasion of his 75th birthday.]

 

62. Bhabak, K. P.; Mugesh, G.* Antithyroid Drugs and their Analogues Protect Against Peroxynitrite-Mediated Protein Tyrosine Nitration- A Mechanistic Study.
Chem. Eur. J., 2010, 16, 1175 - 1185. Read more....
[This work has been featured on the Cover Page of the Journal]

 

61. Sarma, B. K.; Mugesh, G.* Theoretical Investigations on the Effect of Different Nitrogen Donors on Se...N Intramolecular Interactions.
ChemPhysChem, 2009, 10, 3013 - 3020. Read more....

 

60. Bhabak, K. P.; Mugesh, G.* Synthesis and Structure-Activity Correlation Studies of Secondary and Tertiary Amine-based Glutathione Peroxidase Mimics.
Chem. Eur. J., 2009, 15, 9846 - 9854. Read more....

 

59. Bhabak. K. P.; Mugesh, G.* A Synthetic Model for the Inhibition of Glutathione Peroxidase by Antiarthritic Gold Compounds.
Inorg. Chem., 2009, 48, 2449 - 2455. Read more....

 

58. Bhabak, K. P.; Mugesh, G.* Amide-Based Glutathione Peroxidase Mimics: Effect of Secondary and Tertiary Amide Substituents on Antioxidant Activity.
Chem. Asian J., 2009, 4, 974 - 983. Read more....
[Special issue dedicated to Prof. C. N. R. Rao on the occasion of his 75th birthday.]

 

57. Tamilselvi, A.; Mugesh, G.* Inhibition of Peroxidase-catalyzed Iodination by Cephalosporins: Metallo-b-lactamase-induced Antithyroid Activity of Antibiotics.
ChemMedChem, 2009, 4, 512 - 516. Read more....
[This work has been featured on the Cover Page of the Journal]

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